P wave and QT dispersion in pregnant women with Familial Mediterranean fever

Objective Familial Mediterranean Fever (FMF) is the most common hereditary monogenic auto-inflammatory disease. It is characterized by recurrent, self-limited episodes of fever and sterile inflammation of serous membranes. Pregnancy therefore acts as a medical stress test for the mother. This is particularly evident in women who conceive with chronic medical disorders. The limited reserves of an impaired organ will be unmasked and the organ fails to increase its function during pregnancy One of the most important factors that contribute to increased cardiovascular risk appears to be systemic inflammation. Patients with inflammatory rheumatic diseases are now considered to have an increased risk of cardiovascular diseases. Despite its inflammatory nature there are conflicting results as to the association between FMF and increased risk for cardiovascular diseases. It has been never investigated before, any ECG or echocardiographic changes in pregnant with FMF. In this study, we aimed to evaluate of electrical conduction in pregnant women with and without FMF by using ECG and echocardiography.